Ebook Of Organic Synthesis: Strategy and Control 1st Edition by Paul Wyatt and Stuart Warren

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Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice.

The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy.

  • A comprehensive, practical account of the key concepts involved in synthesising compounds
  • Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations
  • Focuses on reactions that really work rather than those with limited application
  • Contains extensive, up-to-date references in each chapter

Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis

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 Brief content Ebook Of Organic Synthesis: Strategy and Control

A: Introduction: Selectivity
1. Planning Organic Syntheses: Tactics, Strategy and Control
2. Chemoselectivity
3. Regioselectivity: Controlled Aldol Reactions
4. Stereoselectivity: Stereoselective Aldol Reactions
5. Alternative Strategies for Enone Synthesis
6 Choosing a Strategy: The Synthesis of Cyclopentenones
B: Making Carbon–Carbon Bonds
7. The Ortho Strategy for Aromatic Compounds
8. σ-Complexes of Metals
9. Controlling the Michael Reaction
1o. Specifi c Enol Equivalents
11. Extended Enolates
12. Allyl Anions
13. Homoenolates
14. Acyl Anion Equivalents
C: Carbon–Carbon Double Bonds
15. Synthesis of Double Bonds of Defi ned Stereochemistry
16. Stereo-Controlled Vinyl Anion Equivalents
17. Electrophilic Attack on Alkenes
18. Vinyl Cations: Palladium-Catalysed C–C Coupling
19. Allyl Alcohols: Allyl Cation Equivalents (and More)
D: Stereochemistry
21. Control of Stereochemistry – Introduction
22. Controlling Relative Stereochemistry Resolution
23. The Chiral Pool — Asymmetric Synthesis with Natural Products asStarting Materials —
24. Asymmetric Induction I Reagent-Based Strategy
25. Asymmetric Induction II Asymmetric Catalysis: Formation of C–O and C–N Bonds
26. Asymmetric Induction III Asymmetric Catalysis: Formation of C–H and C–C Bonds
27. Asymmetric Induction IV Substrate-Based Strategy Kinetic Resolution
28. Enzymes: Biological Methods in Asymmetric Synthesis
29. New Chiral Centres from Old — Enantiomerically Pure
30. Compounds & Sophisticated Syntheses
31. Strategy of Asymmetric Synthesis

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E: Functional Group Strategy
32. Functionalisation of Pyridine
33. Oxidation of Aromatic Compounds, Enols and Enolates
34. Functionality and Pericyclic Reactions: Nitrogen Heterocycles by Cycloadditions and Sigmatropic Rearrangements
35. Synthesis and Chemistry of Azoles and other Heterocycles with Two or more Heteroatoms
36. Tandem Organic Reactions

Review By: Amazon

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